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      • D1 receptor
      • D2 receptor
      • D3 receptor
      • D5 receptor
      • DAT
      • D4 receptor

      DAT 選擇性抑制劑 | 調(diào)節(jié)劑

      目錄號(hào) 產(chǎn)品名 產(chǎn)品描述 Selective / Pan IC50 / Ki
      S6301 MPP+ iodide MPP+ iodide (N-Methyl-4-Phenylpyridinium Iodide), the metabolite of a neurotoxin MPTP, causes symptom of Parkinson's disease (PD) in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ induces autophagic cell death in SH-SY5Y cells. MPP+ induces dopamine transporter (DAT) externalization in dopaminergic (DA) neurons, but internalization of serotonin transporter (SERT) in serotonergic (5-HT) neurons. Selective
      S3163 Benztropine mesylate Benztropine(Cogentin mesylate, Benztropine methanesulfonate) is a dopamine transporter (DAT) inhibitor with IC50 of 118 nM. Selective DAT, IC50: 118 nM
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